Ren M et al. (2020) found that resveratrol (10, 20, 30, 40, 50, 60, 70, 80 μM for 24, 48, 72 h) could synergize with chemotherapeutic drug cisplatin to significantly increase the expression of GRP78, PERK, p-eIF2α, CHOP and cleaved Caspase-12 in GC cells AGS, blocking the cell cycle at G2/M phase and inducing apoptosis. This evidence concerns the gene CASP12 and gastric cancer.