Liu J et al. (2023) reported that isoquercitrin showed to be effective in the treatment of GC cell lines such as HGC-27, AGS, MKN-45 and SNU-1 by upregulating BAX, cleaved Caspase-3 and Caspase-12, and downregulating BCL-2. The gene discussed is CASP12; the disease is gastric cancer.