HSPA5 and cancer: Yan W et al. (2019) reported that salidroside (1,2.5,5,10,25,50,100,250 μM for 48 h) was able to dose-dependently upregulate CHOP and cleaved Caspase-12 levels and significantly downregulate GADD34 and BiP levels in SGC-7901 cells, inhibiting GC cell growth and migration and PI3K/Akt/mTOR thereby promoting cancer cell apoptosis, which can be blocked by autophagy inhibitors.