TP53 and cancer: In recent years, the regulation of autophagy has received much attention in relation to cancer development and treatment (Yamazaki et al., 2021), Ulva intestinalis and Ulva lactuca have been shown to induce autophagic cell death in SiHa cells by up-regulating the expression of Bax and p53 and downregulating the expression of Bcl2, and they also reduced the expression of the viral oncogene HPV-E6 by 1.8 to 2-fold.