The meta-analysis after pooling the data (df = 4, p < 0.00001; I2 = 99%) indicated that the serum MMP-9 level in patients with epileptic seizures was significantly higher than that in the control group (SMD = 5.19, 95% CI = 1.45–8.92, p = 0.006, Figure 3C). The gene discussed is MMP9; the disease is Seizure.