Recent studies have shown that that the serum MMP-9 concentration in epilepsy patients was higher than that in the healthy population, which is consistent with previous reports wherein the serum (Suenaga et al., 2008; Li et al., 2013; Cudna et al., 2017) levels of MMP-9 in epilepsy patients were significantly higher after seizures. Here, MMP9 is linked to epilepsy.