Additionally, the detection of plasma biochemical indices showed that the administration of a high concentration of CS-Neus for 24 h did not result in significant abnormalities in albumin (ALB), aminotransferase (ALT), aspartate aminotransferase (AST), blood urea nitrogen (BUN), and creatinine (CRE), suggesting that CS-Neus do not lead to hepatic and renal dysfunctions (Figure 2D). Here, GPT is linked to Abnormal renal physiology.