We started to analyze the levels of expression of RAB7 and other proteins involved in the endocytic pathway, such as RAB4A, RAB5A, RAB9A, RAB27A, the Rab-interacting lysosomal protein (RILP), the Lysosomal Associated Membrane Protein 1 (LAMP-1), and the V1G1 subunit of the vacuolar ATPase H + Transporting (ATP6V1G1) (Fig. 1B) comparing chemoresistant and chemosensitive ovarian cancer cells. The gene discussed is RAB4A; the disease is ovarian cancer.