They are predicted to contribute to cardiovascular malformations (SUZ12, ADAP2), higher malignant potential (UTP6, ATAD5, SUZ12, RNF135, COPRS, MIR193A, MIR365B), overgrowth (RNF135, SUZ12), intellectual disabilities (OMG, RNF135, SUZ12, CRLF3). The gene discussed is MIR193A; the disease is Intellectual disability.