The rates of myopia progression and axial elongation were 0.47 ± 0.48 D/year and 0.16 ± 0.20 mm/year in NYX, 0.93 ± 0.24 D/year and 0.35 ± 0.10 mm/year in CACAN1F, and 1.35 ± 0.38 D/year and 0.48 ± 0.13 mm/year in TRPM1, respectively, in which the rates of myopia progression and axial elongation were the fastest in patients with TRPM1 variants during 3-year of follow-up (Fig. 4). This evidence concerns the gene TRPM1 and myopia.