For example, the obvious upregulation of MHC-II genes (HLA-DRA, HLA-DPA1, HLA-DPB1, HLA-DQA1, HLA-DMA, HLA-DMB, HLA-DQB1, HLA-DRB5 and HLA-DRB), CD74, and CXCR4 in myeloid cells of the tumor group was accompanied by a high probability of communication between cells in the population of intratumoural myeloid cells. This evidence concerns the gene HLA-DRB5 and neoplasm.