In contrast, the expression of CD62L on these T-cell subsets was significantly lower in podoconiosis patients compared to healthy controls (CD4CD62L, P < 0.0001, with median value of 53.6% vs 63.1%, respectively; CD8CD62L, P = 0.001, with median value of 22.8% vs 36.8%, respectively). Here, SELL is linked to podoconiosis.