TP53 and cancer: Data from the UALCAN database indicated the expressions of IGF2BP3 in GC tumor tissue with different individual cancer stage, tumor grade, nodal metastasis status and TP53 mutation status were all significantly higher than those in normal mucosa tissues respectively, and the expressions of IGF2BP3 in GC tumor tissues with TP53 mutation were upregulated compared to those without TP53 mutation (Fig. S3).