Sanjib Bhattacharyya et al. [95] find that CBS is overexpressed in primary epithelial ovarian cancer and ovarian cancer cell lines, while knockdown of CBS disruptes intracellular energy metabolism, induces elevated ROS, promotes apoptosis and increases numbers of cancer cells killed by cisplatin via reduce NF-κB activity. The gene discussed is NFKB1; the disease is ovarian carcinoma.