Numerous studies have shown that danshinone regulates various molecular pathways in PCa, including signal transducer and activator of transcription 3 pathway, AR pathway, PI3K/AKT/mTOR pathway, mitogen-activated protein kinase pathway, thus affecting the release of proinflammatory cytokines, cell proliferation, apoptosis, and tumor metabolism (10, 11, 12, 13). This evidence concerns the gene AR and posterior cortical atrophy.