The disruption in folliculogenesisobserved in PCOS patients leads to lower fertilization and cleavage rates in thispopulation, and could potentially impair embryo quality and, thus, pregnancy rates(Mashiach et al., 2010).While Mashiach et al. (2010)found that in PCOS patients the FF AMH was related to lower top-quality embryoscompared to controls. This evidence concerns the gene AMH and polycystic ovary syndrome.