We performed a gene set enrichment analysis (GSEA) of 2985 DEGs (1392 upregulated and 1593 downregulated DEGs) obtained from the GSE142582 dataset with the KEGG signaling pathways and found that the IL-17 signaling pathway and cell cycle were associated with the development of psoriasis among the pathways significantly enriched with upregulated genes (Figure 1A). This evidence concerns the gene IL17A and psoriasis.