OPN1LW and panuveitis: For posterior uveitis and panuveitis, toxoplasmosis remained the primary cause; numerous factors contribute to this, including the Colombian geographical localization in a tropical area with high rainfall (pluviosity) [46] and the presence of certain strains with virulence factors like rhoptry virulent-alleles of proteins (ROP) 16 and ROP 18 [40, 41].