Prior to TTVr, patients with RVR had more frequently a history of hospitalization for HF (67% vs. 50%, p = 0.01), diabetes mellitus (31% vs. 14% of patients, p = 0.003), prior myocardial infarction (7% vs. 1%, p = 0.039), higher NT-proBNP level (median 2,627 vs. 1,368 ng/l, p < 0.001), and higher TRI-SCORE (6.5 ± 1.9 vs. 6.0 ± 1.8, p = 0.026). Here, NPPB is linked to hydrops fetalis.