REN and diabetes mellitus: Anaemic patients were slightly older, were more likely to be men, were more symptomatic, and were more likely to have features associated with an adverse prognosis, including diabetes, higher plasma concentrations of N-terminal pro-B-type natriuretic peptide (NT-proBNP), lower estimated glomerular filtration rate (eGFR), treatment with loop diuretics, and lower rates of treatment with renin-angiotensin system antagonists (Table 1).