HAVCR1 and hypertensive disorder: Two cohort studies have reported that urinary KIM1 was not associated with incident hypertension.33,34 In contrast, our present study observed strong positive associations of plasma KIM1 with SBP and hypertension, which is consistent with several cross-sectional studies that have demonstrated positive associations of plasma/serum KIM1 with BP and hypertension.35–37 The difference in biosamples used to measure KIM1 may partially explain these distinct findings.