GPI, GRI and HSPB1 were highly expressed only in myeloid cells of NSCLC with bone metastasis, while HBEGF, HIF1A, MACF1, MMP9, PTGS2 and BEGFA were highly expressed only in myeloid cells of NSCLC with brain metastasis. The gene discussed is HSPB1; the disease is non-small cell lung carcinoma.