The expression of LOX-1 is induced by several pro-inflammatory cytokines (TNF-α, IL-1, IFN-γ), CRP, LPS, modified lipoproteins, hypertension-related stimuli (angiotensin II, endothelin-1, and fluid shear stress), hyperglycemic stimuli (high glucose and AGEs), IL-6, and some other stimuli-like homocysteine and free radicals [48, 61–63]. Here, OLR1 is linked to hypertensive disorder.