According to our KEGG pathways analysis, 17 genes, including ARF6, ABCF2, FYN, JUN, ARHGEF2, WIPF1, ACTB, CLDN1, CLDN11, CLDN16, MAPK1, MYO1F, MYO5A, MYH14, OCLN, PTPN6, and TUBB2A, were enriched in the E. coli infection pathway. Here, ARHGEF2 is linked to escherichia coli infection.