Salvianolic acid A can decrease the expression of LDH in cardiomyocytes, inhibit apoptosis, reduce myocardial infarction size, and play a protective role in I/R injury by inhibiting the dephosphorylation of c-Jun N-terminal kinase (JNK) mediated by dual-specificity phosphatase 2 (DUSP2) and activating the phosphorylation of ERK1/2 mediated by DUSP4/16 [144]. The gene discussed is DUSP2; the disease is myocardial infarction.