In the present study, through an analysis of differential mRNA expression, we identified several upregulated genes associated with peritoneal fibrosis, including TWIST1, TWIST2, ZEB1, ZEB2, SNAI1, and SNAI2. Twist reportedly contributes to peritoneal fibrosis during PD treatment by regulating YB-1 [40]. The gene discussed is TWIST1; the disease is Peritoneal Fibrosis.