In the present study, through an analysis of differential mRNA expression, we identified several upregulated genes associated with peritoneal fibrosis, including TWIST1, TWIST2, ZEB1, ZEB2, SNAI1, and SNAI2. Twist reportedly contributes to peritoneal fibrosis during PD treatment by regulating YB-1 [40]. Here, YBX1 is linked to Peritoneal Fibrosis.