FGF19, FGF21 and GDF-15 were measured in blood samples using ELISA.<h4>Results</h4>SAGEs were elevated in both groups of patients with diabetes as compared to healthy controls (both p < 0.001) and were higher in patients with DM2 in comparison to DM1 (p = 0.006). The gene discussed is FGF19; the disease is diabetes mellitus.