Mean CRP was significantly higher in RA (26.38 ± 29.14) than in FDRs (5.99 ± 5.08, p < 0.001) and controls (2.02 ± 0.53, p < 0.001) and significantly higher in FDRs than in controls (p = 0.011). The gene discussed is CRP; the disease is rheumatoid arthritis.