Compared with patients without FH, those with definite/probable and possible FH were younger but showed higher TC (8.29, 5.54 vs. 3.76 mmol/L, P < 0.001), LDL-c (5.62, 4.07 vs. 2.29 mmol/L, P = 0.001), apoB (0.95, 0.95 vs. 0.84 g/L, P = 0.004), Lp(a) (29.0, 19.8 vs. 11.3 mg/dL, P = 0.007), non-HDL-c (7.09, 4.47 vs. 2.70 mmol/L, P < 0.001), TC/HDL-c ratio (7.67, 5.37 vs. 3.63, P < 0.001) and apoB/apoA1 ratio (0.86, 0.73 vs. 0.65, P < 0.001) (Table 1). The gene discussed is APOA1; the disease is familial hyperaldosteronism.