Interneurons have garnered attention as pivotal components for understanding the neural circuits involved in epilepsy, with particular focus on the three main interneuron populations in the rodent hippocampus: parvalbumin (PV), somatostatin (SST), and vasoactive intestinal peptide expressing interneurons (Miles et al. 1996; Paz and Huguenard 2015; Lovett-Barron et al. 2012). This evidence concerns the gene SST and epilepsy.