Among them, engineered NK-92 cells expressing a hybrid receptor (named TN-chimeric), which is composed of the extracellular part of TGFβRII and the transmembrane and intracellular domains of NKG2D, exhibited enhanced chemoattraction to tumor cells expressing TGF-β and had enhanced killing ability (Fig. 2) [148]. This evidence concerns the gene TGFB1 and neoplasm.