UHMK1, RALYL, MGST3, USP9X, ESRG are directly related with the drug resistance phenotype, while SPINK13, LINC00664, MRPL38, EMILIN3 do not have a direct relationship with drug resistance in cancer, but there are other genes that belong to the same family that are known to be involved in drug resistance. This evidence concerns the gene ESRG and cancer.