To further confirm the relevance of LDHA-mediated tumor glycolysis in promoting macrophage infiltration, we conducted shRNA-mediated LDHA depletion (shLdha) in glioblastoma cells, such as CT2A and GL261 (Fig. 2d), or treated them and GSCs with LDHA inhibitors (e.g., stiripentol and FX11). This evidence concerns the gene LDHA and neoplasm.