Analysis of the scRNA-seq data34 also identified LDHA as the only gene that was increased in glioma cells of glioblastoma (including ndGBM and rGBM) compared to LGG (Fig. 2a) and correlated positively with the abundance of macrophages and monocytes in glioblastoma patient tumors (Fig. 2b). Here, LDHA is linked to glioma.