To reveal the importance of these genes in glioblastoma tumor biology, we conducted bioinformatics analyses in TCGA glioblastoma tumors showing that the expression of most of these genes (except for NPY) correlated positively with macrophage signature, but only CCL2, CCL7, IL1RAP, PLAU, and S100A8 correlated negatively with patient survival (Supplementary Fig. S5a). This evidence concerns the gene IL1RAP and glioblastoma.