BCL2 and leukemia: Only one gene, BCL2, had a significant positive association (FDR of <10%), involving 29 lymphomas and two leukemias, which association involved an already well-known translocation t(14; 18) juxtaposing BCL2 to the immunoglobulin heavy chain gene enhancer at band 14q32, resulting in gene over-expression and inhibition of apoptosis.30