Ex vivo tissue section autoradiography experiments showedthat this radiotracer (2-((4-(aminomethyl)benzyl)oxy)-4-(4-[18F]fluorophenyl)thiophene-3-carbonitrile) exhibited a 1.4-fold higheruptake in PD-L1+ compared to PD-L1– H358tumors (lung adenocarcinoma). This evidence concerns the gene CD274 and lung adenocarcinoma.