TWIST1 and Saethre-Chotzen syndrome: When the gene Twist1 that is mutated in Saethre-Chotzen syndrome is knocked out in Ctsk-lineage cells, it recapitulates the signature craniosynostoiss phenotype associated with Twist1 loss (Bok et al., 2023; Maruyama, 2019; Yu et al., 2021).