For example, as the biomarker of the Cluster 2 subtype and the predictor of good survival, Flammeovirga, Lachnoclostridium, Terrabacter, Gelidibacter, Pseudogulbenkiania, and Nitrospira were positively correlated with the anti-tumor immune cells, including NK cells and CD4 and CD8 cells, but negatively associated with CD8 naïve cells and monocyte cells. The gene discussed is CD4; the disease is neoplasm.