Furthermore, after transfer into LLC1-OVA tumor–bearing mice, the greatest numbers of IFN-γ–producing intratumoral CD8+ T cells were observed in mice that received A2ARi-treated GCLC-overexpressing CD8+ T cells (Figure 2P) accompanied by a decrease in tumor burden compared with other groups of mice (Figure 2Q). This evidence concerns the gene IFNG and neoplasm.