Furthermore, in 499 pwMS receiving interferon-beta as first DMT, interferon-beta discontinuation was more frequent in female pwMS than in male pwMS (HR 1.42) [28].These results were confirmed by another study, which showed that women were more likely to stop interferon-beta or glatiramer acetate initiated after MS diagnosis than men [29]. The gene discussed is IFNB1; the disease is myeloid sarcoma.