Firstly, we evaluated the expression profile of MXRA8 in both prostate cancer tissue and adjacent normal tissues using PCR, immunohistochemistry and western blot techniques, where we observed a significant upregulation of MXRA8 in prostate cancer samples as compared to their normal counterparts (Figure 15A, 15B, 15H). This evidence concerns the gene MXRA8 and Familial prostate cancer.