Importantly, depletion of PDAP1 in B cells also caused a sustained expression of ATF4 and induction of ATF4 stress response transcriptional program,[62] and our data showed that PDAP1 depletion in basal‐like breast cancer induced ferroptotic cell death and significantly reduced tumor growth in xenograft model (Figure 4). This evidence concerns the gene PDAP1 and breast carcinoma.