As FcRn is important for IgG transcytosis and translocation of IgG‐opsonized antigen in mucosal tissues12, 13, 30, 31, 32, 33 and has a pivotal role in IgG transcytosis in the mammalian female reproductive tract,9 we sought to further investigate the role in infection and pathology in a FcRn−/− mouse model. The gene discussed is FCGRT; the disease is infection.