Conversely, infection with IgG‐opsonized Chlamydia led to the upregulation of mRNA for chemokines and cytokines Ccl2, Ccl5/RANTES, Ccl8/MCP‐2, Il6 (highest, 5928‐fold), Csf2/GM‐CSF and Ifnγ; antigen processing and chemotaxis Cd2, Cd40, H2‐DMa/MHC‐2, Icam1 and Icam2 (highest, 744‐fold); and signal transduction Flt3I (37‐fold). This evidence concerns the gene CD40 and infection.