In addition to Fas-dependent autophagy pathway activation, the study revealed heightened activity of crucial components related to mitochondria-dependent apoptosis, such as Bax, Bax-to-Bcl-2 ratio, cytosolic cytochrome c, activated caspase-9, and activated caspase-3, in HD mice compared to wild-type mice. The gene discussed is BAX; the disease is Huntington disease.