Hematoxylin-eosin (HE) staining exhibited that, compared with the DDP group, the tumor tissue appeared to have disorganized cell arrangement, with different degrees of necrosis and infiltration of inflammatory cells in the OV-TP53 group, and this pathological change was reversed in the OV-TP53+OV-miR-424-5p group (Fig. 6E). This evidence concerns the gene TP53 and neoplasm.