It has been shown that downregulation of miR-142-3p resulted in upregulation of CD39 in regulatory T (Treg) cells [54], and miR-30a-5p can bind directly to the 3′-untranslated regions (UTR) of CD73 mRNA, subsequently reducing its expression in colorectal, NSCLC and pancreatic cancers [55–57]. The gene discussed is ENTPD1; the disease is familial pancreatic carcinoma.