KIF3C and Miyoshi myopathy: The qRT-PCR and WB results revealed that both KIF3C mRNA and protein levels were increased in PI-resistant KAS-6/1 and U266 cells compared to PI-sensitive KAS-6/1 and U266 cells (Supplementary Figure S17 and Fig. 8F), indicating that KIF3C should originate from the genomic DNA in PI-sensitive MM cells while originate from the genomic DNA and eccDNA in PI-resistant MM cells.