We included gender, age, duration, smoking history, alcohol consumption history, history of hypertension, medication use (hypoglycemic drugs, antihypertensive drugs, statins), BMI, SBP, DBP, FBG, HOMA-IR, HbA1C, TC, TG, LDL, HDL, UA, Cr, NLRP3, MALAT1 as independent variables and the occurrence of LEAD as the dependent variable in the LASSO regression model for variable screening. This evidence concerns the gene NLRP3 and hypertensive disorder.