NLRP3 and type 2 diabetes mellitus: ROC analysis was also used to compare the predictive value of individual parameter indicators in the model, and the AUC of MALAT1 and NLRP3 for predicting combined LEAD in T2DM patients were 0.804 and 0.794, which were greater than those of age (AUC = 0.715), SBP (AUC = 0.596), and smoking (AUC = 0.550).