The immune molecule expression levels in tumor tissues showed that the mRNA expression levels of CD44 (P > 0.05), Ccr7 (P < 0.05) and L-selelctin (P < 0.05) were increased in the E6E7 group compared with the PBS group or LM∆ & LI∆ group (Fig. 5E-G), and the mRNA expression level of Eomes was slightly higher (P > 0.05) (Fig. 5H). Here, CD44 is linked to neoplasm.