CYP4A22-rs2056900 was significantly associated with increased risk of CHD (allele: OR, 1.22; 95%CI, 1.02–1.46; p-value is 0.032; codominant: OR, 1.49; 95%CI, 1.04–2.14; p-value is 0.032; recessive: OR, 1.42; 95%CI, 1.06–1.91, p-value is 0.020; and log-additive: OR, 1.22; 95%CI, 1.02–1.46; p-value is 0.031). The gene discussed is CYP4A22; the disease is coronary artery disorder.