TCF7 and acute myeloid leukemia: Since it has previously been reported that BETi treatment of AML cells leads to transcriptional upregulation of Wnt signaling pathway components [16, 17], we next examined mRNA expression of CTNNB1, the gene encoding for β-catenin, as well as the Wnt receptor FZD1, CDK14, GSK3β, AXIN2, and the TCF/LEF transcription factors TCF4 and TCF7 in MV4-11, MOLM-13, and OCI-AML3 cell lines following treatment with dinaciclib, PLX51107, or the combination.