Moreover, 10 of the 30 acute episodes who had symptoms of both MOGAD and anti-NMDAR encephalitis were positive for both blood MOG antibodies and CSF anti-NMDAR, seven (23.3%) showed as anti-NMDAR encephalitis symptoms only (such as abnormal psychiatric behavior, sleep disorder and cognitive dysfunction), and nine (30%) showed as MOGAD symptoms only(such as visual impairment, headache and consciousness disturbance). This evidence concerns the gene MOG and sleep disorder.