We created a highly accurate (c-index 0.87) long-term prognostic scoring system called the CACHEXIA score (Cancer including metastasis tumor, blood tumor, and bleeding from tumor, Albumin, Cirrhosis, High PS, EXtremely thin (i.e., low BMI), Increased CRP and BUN, Anemia (i.e., blood transfusion)). The gene discussed is CRP; the disease is anemia (phenotype).