ANKRD1 and pheochromocytoma: Here, we found a significant decrease in the DNA methylation level of ANKRD1 in BLCA, BRCA, CESC, CHOL, COAD, HNSC, KIRC, KIRP, LIHC, LUAD, LUSC, OV, PAAD, pheochromocytoma and paraganglioma (PCPG), READ, THCA, and UCEC based on the TCGA database (Fig. 4A).