When examining the relationship between ANKRD1 expression and essential MMR signatures (PMS1 homolog 2 (PMS2), MutL homolog 1 (MLH1), MutS homolog 2 (MSH2) and MutS homolog 6 (MSH6), and epithelial cell adhesion molecule (EPCAM)), significant associations were observed in most cancers, except ACC, CHOL, DLBC, KICH, KIRC, OV, SARC, STAD, and UVA (Fig. 10). The gene discussed is MLH1; the disease is cancer.